ORIGINAL ARTICLES   

International Angiology 2012 October;31(5):438-43

Copyright © 2012 EDIZIONI MINERVA MEDICA

language: English

Surgery for ruptured abdominal aortic aneurysm and early mortality in women. Risk factors and complication profile

Berge C. ^{1, 2}, Hagen A. I. ², Myhre H. O. ^{1, 2}, Haug E. S. ³, Dahl T. ^{1, 2} ✉

¹ Department of Circulation and Medical Imaging; Norwegian University of Science and Technology, Trondheim, Norway; ² Department of Surgery, University Hospital of Trondheim, Norway; ³ Department of Urology, Vestfold Hospital, Tønsberg, Norway

AIM: Repair of ruptured abdominal aortic aneurysm (rAAA) is reported to have a higher mortality in women than in men. The aim was to study whether this difference could be verified in our institution and secondary if difference in risk- and complication profiles could explain the higher 30 day mortality after surgery for rAAA in women.
METHODS: During the period 1983-2009 1649 patients, 1348 men and 301 women, were operated consecutively for infrarenal abdominal aortic aneurysm (AAA); 430 patients had rAAA, 98 women and 332 men. Co-morbidities were identified from the patients’ medical records. Outcome measures within 30 days were mortality, cardiac disease (heart attack, heart failure), cerebrovascular disease (stroke, TIA), renal insufficiency (serum creatinine >140 µmol/L), major amputation, bowel infarction, pancreatitis and graft related complications.
RESULTS: Compared to men, women had higher 30 d mortality after surgery for rAAA (54.1% vs. 36.3%, P=0.002). Women were significantly older than men (76 years vs. 73 years, P=0.001). In the period 1995-2009 women had more autoimmune diseases than men (P=0.045). There was no significant difference between men and women for the other measured outcomes.
CONCLUSION: During the period 1995-2009, autoimmune disease were more common among women than men. For all other parameters recorded, there were no differences in risk – or complication profile that could explain the higher 30 d mortality in female patients after surgery for rAAA.