ORIGINAL ARTICLE  EPIDEMIOLOGY AND CLINICAL MEDICINE 

The Journal of Sports Medicine and Physical Fitness 2017 May;57(5):633-42

DOI: 10.23736/S0022-4707.16.06092-8

Copyright © 2016 EDIZIONI MINERVA MEDICA

language: English

Acute effects of aerobic, resistance and concurrent exercises, and maximal shuttle run test on coagulation and fibrinolytic activity in healthy young non-athletes

Amir AMINI ¹, Vahid SOBHANI ¹, Mohammad T., MOHAMMADI ², Hossein SHIRVANI ¹ ✉

¹ Exercise Physiology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran; ² Department of Physiology and Biophysics, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran

BACKGROUND: The present study aimed to differentiate the acute effects of aerobic, resistance and concurrent exercises, and 40-meter maximal shuttle run test (MSRT) on coagulation and fibrinolysis in non-athletic healthy young men.
METHODS: Fifty participants (aged 20-30 years old) were randomly divided into a control and four exercise groups: aerobic, resistance, concurrent, and MSRT (N.=10 each). A single session of exercise was performed: the aerobic group used a cycle ergometer (60% heart rate maximum) for 40 minutes, the resistance group performed 3 movements for the upper extremities and 3 movements for the lower extremities with 60% of 1-repetition maximum (each movement in 2 sets of 8-10 repetitions), the concurrent group followed by a combination of aerobic and resistance protocols, and the MSRT group performed four trials of the 40-meter MSRT. The duration for aerobic, resistance and concurrent exercises was 60 minutes, while it was only 30 minutes for MSRT. Before and 30 minutes after exercise, blood samples were collected to evaluate fibrinogen (mg/dL), D-dimer (mg/dL), prothrombin time (PT), partial thromboplastin time (PTT) and platelet count (×103/µL).
RESULTS: There was a significant reduction in fibrinogen in all exercise groups compared to before exercise (P<0.01) and to the control group (P<0.05). D-dimer, as the index of fibrinolysis, was significantly increased in all exercise groups compared to before exercise (P<0.01) and to the control group (P<0.05). Aerobic exercise and MSRT also increased the PT and PTT (P<0.001). Finally, the number of platelets had a significant reduction following resistance and concurrent exercise protocols (P<0.001, P<0.01).
CONCLUSIONS: Based on our findings, both coagulation and fibrinolytic activity are strongly affected by single a session of different exercise protocols.

KEY WORDS: Blood coagulation - Fibrinolysis - Exercise - Fibrin fragment D - Fibrinogen