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Chirurgia 2025 April;38(2):106-11

DOI: 10.23736/S0394-9508.24.05829-7

Copyright © 2024 EDIZIONI MINERVA MEDICA

language: English

The next milestone in bioactive ion-releasing dental resin composite

Khaled A. ALTHAQAFI

College of Dental Medicine, Department of Restorative Dentistry, Faculty of Dentistry, Ummul Al Qura University, Makkah, Saudi Arabia



One of the main reasons resin-based dental restoration fail is secondary caries. Numerous studies have investigated adding a number of bioactive substances to resin-based materials in order to stop bacteria from attaching to biofilms and causing secondary caries. The term bioactivity is becoming more used in medicine and dentistry. However, the term’s meaning is still unclear. The aim was to concentrate on applications of various remineralization techniques, along with how they are applied to various restorative materials. This review concentrated on remineralizing substances in various restorative materials, including organic agents, metallic particles, nanotubes, and bioactive substances with antibacterial qualities like quaternary ammonium. Only English-language articles published from 2018 to April 2024 were selected from PubMed and Medline used in the review. This review research study was founded on the recommendations of the PRISMA statement for writing systematic reviews studies. Every bioactive formulation is designed to improve the performance of the desired material by retaining basic functionality while increasing bioactivity. Despite the improvements, there are still numerous hurdles to face, and the majority of the research is in their early stages of development. Further evaluation will be required for future clinical translation.


KEY WORDS: Composite resins; Regeneration; Surgical procedures, operative

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