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Recurrent cystitis

Prompt diagnosis risk stratification and management

Tommaso CAI

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DESCRIPTION

Major work has been done unraveling the genomes of major bacterial classes, highlighting the nature and importance of the microbiome, also in previously sterile sites such as the urine, elucidating the immune system in the different compartments, such as the urinary tract. We have learned an enormous amount of information about host-pathogen interaction, microbial factors, and the immune system. According to these principles the recent Covid-19 pandemic has created an enormous collaborative work, resulting in outstanding successes, such as developing test systems and vaccines in previously unbelievable short times. This book approaches one of the most frequent infections. Apart from the issue of antimicrobial resistance, which is accompanied by the frequent antibiotic treatments in this patient population, the affected persons suffer severe psychosocial consequences amongst others. The authors target recurrent cystitis from various angles, highlighting classification systems, epidemiology, diagnostic strategies, risk factors, microbiological corner stones, and therapeutic principles, including antibiotic sparing strategies. Recurrent cystitis is not simple to treat, but calls for an encompassing management, keeping in mind not only the individual patient’s outcome, but also the endpoints of microbiome preservation and prevention of antimicrobial resistance.


ABOUT THE AUTHORS

Tommaso CAI. Department of Urology, Santa Chiara Regional Hospital, Trento, Italy; Institute of Clinical Medicine, University of Oslo, Oslo, Norway


CHAPTER INDEX

CLASSIFICATION OF URINARY TRACT INFECTION: FROM THE ORENUC SYSTEM TO THE CLINICAL PRACTICE

Paolo Verze, Luigi Napolitano, Belmonte Mario

EPIDEMIOLOGY AND THERAPEUTIC APPROACH TO ACUTE UNCOMPLICATED UTI

Alejandro Garcia-Larrosa

DIAGNOSTIC TOOLS FOR UTI: A CLINICAL PRACTICE-GUIDED APPROACH

Ivan S. Palagin

RECURRENT UTI: THE BURDEN OF THE DISEASE

Maria Angela Cerruto, Alessandro Tafuri

RECURRENT UTI AND RISK FACTORS: WHEN PROMPT IDENTIFICATION MAKES ALL THE DIFFERENCE

Tommaso Cai, Adrian Pilatz, Gernot Bonkat, Florian M. E. Wagenlehner, Truls E. Bjerklund Johansen

RECURRENT UTI: THE MICROBIOLOGIST POINT OF VIEW

Sandra Mazzoli, Tommaso Cai

THE ROLE OF THE MICROBIOTA IN THE GENESIS OF RECURRENCE

Daniele Mattevi, Lorenzo G. Luciani

THE THERAPEUTIC APPROACH TO RECURRENT UTI: WHAT THE EAU GUIDELINES SUGGEST

José Medina-Polo

IS THERE A PLACE FOR ANTIBIOTIC PROPHYLAXIS?

Caterina Palleria, Gregorio La Cava, Michele Palumbo, Lucia Muraca, Giovambattista De Sarro, Luca Gallelli

THE ROLE OF ANTIBIOTIC-SPARING APPROACHES TO RECURRENT UTI: WHAT IS NEW?

Davide Arcaniolo, Lorenzo Spirito, Celeste Manfredi

RECURRENT UTI PREVENTION: TREAT THE BOWEL TO TREAT THE BLADDER

Irene Tamanini, Umberto Anceschi, Stefano Chiodini, Tommaso Cai

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