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Medical treatment of Benign Prostatic Hyperplasia
Massimo PORENA
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DESCRIZIONE
The medical therapy for benign prostatic hyperplasia has a short history, which started no farther back than 25-30 years ago. Before then, surgery was the only real treatment for prostatic disease aimed at also resolving the associated lower urinary tract symptoms (LUTS). Nowadays, several drugs are available for the treatment of prostatic enlargement, which stop or minimize glandular growth, improve bladder neck and urethral hypertonicity or reduce the associated LUTS. They can be used as a monotherapy or in various combinations. This book is meant to be a summary of the latest developments in the management of benign prostatic hyperplasia and a guide to the use of drugs, focusing on their biological mechanisms of action and their adverse events. The Authors involved in this work are the back-bone of research in this field in Italy. Therefore this is an indispensable reference book useful to fellows and specialists in urology.
INFORMAZIONI SUGLI AUTORI
Massimo PORENA. Urology and Andrology Clinic, Santa Maria della Misericordia Hospital, Sant’Andrea delle Fratte, Perugia, Italy
INDICE DEI CAPITOLI
ETIOPATHOGENETIC AND PATHOPHYSIOLOGIC PATHWAYS
M. Porena, E. Costantini, A. Giannantoni, L. Mearini
CLINICAL ENDPOINTS OF MEDICAL TREATMENT, INDICATIONS AND PATIENT SELECTION
A. Tubaro, C. De Nunzio, F. Esperto, F. Presicce
MEDICAL TREATMENT - α1-blockers
M.A. Cerruto, C. D’Elia, W. Artibani
MEDICAL TREATMENT - Androgen manipulation: 5-α-reductase inhibitors, other antiandrogens, aromatase inhibitors (antiestrogens)
M. Carini, M. Gacci, P. Spatafora, S. Serni
MEDICAL TREATMENT - Treatment of symptoms related to BPH: anticholinergics (antimuscarinics), phosphodiesterase-5 inhibitors, β3-agonists
G. Guazzoni, M. Lazzeri
MEDICAL TREATMENT - Combination therapy in BPH
V. Mirone, M. Franco, R. La Rocca, L. Venturino, A. Palmieri
MEDICAL TREATMENT - Phytotherapy and nutraceuticals
G. Morgia, D. Urzì, G.I. Russo