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Metastatic breast cancer

Treatment and management

CURIGLIANO G.; DE LAURENTIIS M.

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DESCRIZIONE

Breast cancer is a complex disease that affect millions of people worldwide, and despite significant advances in the understanding and treatment of this disease, metastatic breast cancer remains a major clinical challenge. The development of new drugs and treatment approaches is crucial to improve the outcomes and quality of life of patients with advanced breast cancer. This book aims to provide a comprehensive overview of the current state of the art in the development of new drugs for metastatic breast cancer. It brings together leading experts form various fields, including clinical oncology, basic science, pharmacology, and drug development, to share their knowledge and experience in the development of novel therapeutic strategies. The book covers a wide range of topics, including the biology of metastatic breast cancer, the current standard of care, and the emerging therapeutic targets and approaches. It also provides an in-depth analysis of the clinical trials and the latest data on the efficacy and safety of the new drugs in development. The authors hope that this book will serve as a valuable resource for clinicians, researchers, and students interested in the field of breast cancer research and drug development.



INDICE DEI CAPITOLI

Biology - Breast cancer subtypes

Stefania Morganti, Antonio Marra

Biology - Breast cancer: the process of metastasis

Annalisa Cristão, Nicola Normanno

Biology - Genomic landscape of metastatic breast cancer

Antonio Marra

Biology - Immunology of breast cancer: basic concepts and a brief overview

Maria Gion, Cristina Saavedra, Maria San Roman Gil, Javier Cortes

Biology - Biomarkers in metastatic breast cancer

Luca Malorni, Ilenia Migliaccio

Biology - Liquid biopsy in metastatic breast cancer

Giulia Viale, Luca Licata, Giampaolo Bianchini

Imaging - PET/CT in metastatic breast cancer

Secondo Lastoria, Luciano Carideo, Marco Raddi, Alfredo Rossi

Imaging - Whole-body MRI in metastatic breast cancer

Giuseppe Petralia, Fabio Zugni, Roberta Maggioni, Paul Eugene Summers

Treatment - General strategy

Grazia Arpino, Simone Carrano, Fabrizio Di Costanzo, Gennaro Iengo

Treatment - Hormone receptor-positive metastatic breast cancer

Lucia Del Mastro, Maria Maddalena Latocca

Treatment - HER2-positive metastatic breast cancer

Filippo Montemurro, Giovanna Chilà, Elena Geuna, Danilo Galizia

Treatment - Metastatic triple negative breast cancer outline

Carla Corvaja, Mattia Garutti, Lorenzo Gerratano, Fabio Puglisi

Treatment - HER2-low breast cancer and other non-typical subtypes

Paolo Tarantino

Treatment - Locoregional therapy

Rosa Di Micco, Emanuela Esposito, Sara Falivene, Giulia Gasparini, Oreste Davide Gentilini

Treatment - Oligometastatic disease

Alessandra Fabi, Antonio Franco, Vittoria Barberi, Fabio Marazzi

Complications - Bone metastases

Michele Iuliani, Francesco Pantano, Luigi Rossi, Gianpaolo Spinelli, Marianna Cerro, Federica Riva, Federica Gatti, Silvia Cavaliere, Giuseppe Tonini, Daniele Santini

Complications - Lung metastases

Vincenzo Di Lauro, Martina Pagliuca, Roberta Caputo

Complications - Liver metastases

Sara Parola, Rossana Di Rienzo, Roberto Buonaiuto, Carmine De Angelis

Complications - CNS metastases

Aldo Caltavituro, Claudia Martinelli, Angela Pizzuti, Mario Giuliano 186

Complications - Metabolic complications

Roberto Buonaiuto, Claudia Calderaio, Giuseppe Buono

Complications - Pain

Claudia von Arx

Complications - Cachexia

Claudia Calderaio, Giuseppe Buono

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