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THE JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS

Rivista di Medicina, Traumatologia e Psicologia dello Sport


Indexed/Abstracted in: Chemical Abstracts, CINAHL, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
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The Journal of Sports Medicine and Physical Fitness 2017 Nov 17

DOI: 10.23736/S0022-4707.17.06763-9

Copyright © 2017 EDIZIONI MINERVA MEDICA

lingua: Inglese

Evaluation of anabolic steroid induced renal damage with sonography in bodybuilders

Umut H. KANTARCI 1 , Zekine PUNDUK 2, Omer SENARSLAN 3, Alper DIRIK 4

1 Department of Radiology, Esrefpasa Hospital, Izmir, Turkey; 2 Department of Physical Education and Sports, Balikesir University, Balikesir, Turkey; 3 Department of Cardiology, Special Medifema Hospital, Izmir, Turkey; 4 Department of Urology, Special Ege Sehir Hospital, Izmir, Turkey


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BACKGROUND: The aim of this study was to investigate the effect of anabolic steroids on kidneys in bodybuilders.
METHODS: Twenty two bodybuilders were included in the study. Participants were divided into three groups according to the scheme of steroid usage: Group 1 (n=8, intramuscular 500 mg testosterone enanthate, intramuscular 400 mg nandrolone decanoate and oral 40 mg methandrostenolone for 12 weeks), Group 2 (n=7, intramuscular 500 mg testosterone enanthate, intramuscular 300 mg nandrolone decanoate and intramuscular 300 mg boldenone undecylenate for 16 weeks) and Group 3 (n=7, no steroid intake). Blood urea nitrogen (BUN), creatinine (Cr), urine microalbumin and electrolyte levels were measured. Renal volume, cortical thickness and echogenicity were obtained in ultrasonographic scans.
RESULTS: Renal volume, cortical thickness, echogenicity and protein intake value were significantly higher in group 2 than group 1 and 3. Plasma levels of BUN and Cr in group 2 were significantly higher than other groups (p ˂ 0.001). Urine microalbumin and electrolyte levels were normal in all groups.
CONCLUSIONS: The results of this study indicate that high protein intake, steroid usage, particularly the schemes, including boldenone undecylenate increases cortical echogenicity, thickness of renal parenchyma and renal volume in bodybuilders.


KEY WORDS: Steroids - Bodybuilders - Renal damage - Kidney grade - Protein intake

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Publication History

Article first published online: November 17, 2017
Manuscript accepted: November 8, 2017
Manuscript revised: October 26, 2017
Manuscript received: June 12, 2016

Per citare questo articolo

Kantarci UH, Punduk Z, Senarslan O, Dirik A. Evaluation of anabolic steroid induced renal damage with sonography in bodybuilders.. J Sports Med Phys Fitness 2017 Nov 17. DOI: 10.23736/S0022-4707.17.06763-9

Corresponding author e-mail

drumutkantarci@gmail.com