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The Journal of Sports Medicine and Physical Fitness 2018 October;58(10):1519-24

DOI: 10.23736/S0022-4707.17.07202-4


lingua: Inglese

Variation in plasma cytokine concentration during a training season in elite kayakers

Grasiely F. BORGES 1, 2, Luis RAMA 1, Humberto M. CARVALHO 3, Joana GASPAR 4, Amandio SANTOS 1, Alain MASSART 1, Beatriz GOMES 1, Luciele G. MINUZZI 1, Artur PAIVA 5, Ana M. TEIXEIRA 1

1 Center for Sport and Physical Activity, Faculty of Sport Sciences and Physical Education, University of Coimbra, Coimbra, Portugal; 2 Federal University of Southern Bahia, Ferradas, Itabuna, Brazil; 3 Faculty of Physical Education, University of Campinas - UNICAMP, Campinas, Brazil; 4 Laboratory of Cell Signaling, University of Campinas - UNICAMP, Campinas, Brazil; 5 Flow Cytometry Unit-Clinical Pathology Service, University Hospital Center of Coimbra, Coimbra, Portugal


BACKGROUND: The purpose of this study was to investigate the differences in cytokines levels in the peripheral blood of kayakers at different moments of training.
METHODS: The sample comprised 12 elite kayakers preparing for the Beijing Olympic Games. Blood samples were collected at different time points of the training season: baseline (t0-November) after 6 weeks of off-training and before the start of the training season; t1 (January) at week 11 after a period of high-volume training; t2 (April) at week 26 at the end of a period of high intensity training sessions; t3 (June) at week 31 after a competitive period.
RESULTS: Decreases in cytokine levels were found for IL-1β and IL-18 at t1. IL-1 then increased throughout the remaining training season while IL-18 leveled off towards the end of the season. IL-1ra showed an exponential increase at t2 before leveling-off in the last period of training. No significant changes were found for IL-6, IFN-γ and TNF-α. No differences were observed in the magnitude and pattern of cytokines changes across the training season between the elite female and male kayakers.
CONCLUSIONS: Increases in training volume were able to induce decreases in pro-inflammatory plasma cytokine coinciding with the reported increase in upper respiratory tract infections in the kayakers.

KEY WORDS: Athletes - Cytokines - Respiratory system

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