Home > Riviste > The Journal of Sports Medicine and Physical Fitness > Fascicoli precedenti > The Journal of Sports Medicine and Physical Fitness 2003 December;43(4) > The Journal of Sports Medicine and Physical Fitness 2003 December;43(4):535-8

ULTIMO FASCICOLO
 

JOURNAL TOOLS

eTOC
Per abbonarsi
Sottometti un articolo
Segnala alla tua biblioteca
 

ARTICLE TOOLS

Estratti
Permessi

 

Original articles  PHARMACOLOGY 

The Journal of Sports Medicine and Physical Fitness 2003 December;43(4):535-8

Copyright © 2009 EDIZIONI MINERVA MEDICA

lingua: Inglese

Oral theophylline supplementation and high-intensity intermittent exercise

Pigozzi F., Sacchetti M., Di Salvo V., Alabiso A., Fagnani F., Parisi A.

University Institute of Movement Sciences (IUSM), Rome Italy,


PDF


Aim. The ­present ­study was car­ried out to inves­ti­gate wheth­er ­oral theo­phyl­line sup­ple­men­ta­tion ­exerts an ergo­gen­ic ­effect dur­ing inter­mit­tent ­high-inten­sity exer­cise.
Methods. Ten ­healthy sub­jects under­took inter­mit­tent exer­cise (1 min ­cycling at 120% of V.O2max ­with 3 min of recov­ery ­until exhaus­tion). The exer­cise ­test was repeat­ed ­twice, 1 ­week ­apart. On ­each occa­sion, the sub­ject ingest­ed, in a dou­ble ­blind set­ting, ­either theo­phyl­line (4.5 mg/kg) or pla­ce­bo 90 min ­before com­menc­ing the exer­cise ­test.
Results. Three sub­jects ­could not com­plete ­both ­trials due to nau­sea and diz­zi­ness ­after theo­phyl­line had ­been admin­is­tered. Time to exhaus­tion in the remain­ing sub­jects was slight­ly ­increased ­after theo­phyl­line admin­is­tra­tion (55.9±6 min vs 59.3±5.9 min; p<0.05).
Conclusion. ­Present ­data indi­cate ­that ­oral theo­phyl­line sup­ple­men­ta­tion ­delays ­fatigue ­onset dur­ing inter­mit­tent ­high-inten­sity exer­cise. The ­effect, ­although sta­tis­ti­cal­ly sig­nif­i­cant, ­does not ­appear to be ­marked. The pos­sibil­ity of occur­rence of neg­a­tive ­side ­effects and the evi­dence for its ergo­gen­ic poten­tial sug­gests the neces­sity to ­include theo­phyl­line in the International Olympic Committee (IOC) World Antidoping Agency (­WADA) ­list as a ­banned or restrict­ed sub­stance.

inizio pagina