MENOPAUSE IN 2014 

Panminerva Medica 2014 December;56(4):273-83

Copyright © 2014 EDIZIONI MINERVA MEDICA

lingua: Inglese

Osteoporosis therapies in 2014

Litwic A. ¹, Cooper C. ^{1, 2}, Dennison E. ¹ ✉

¹ MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK; ² IHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, UK

Osteoporosis is a systemic disorder characterized by low bone mass and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture. It has a significant impact on public health through the increased morbidity, mortality, and economic costs associated with fractures. Despite the severe medical and socioeconomic consequences of fragility fractures, relatively few adults with fractures are evaluated and/or treated for osteoporosis. In this review, we summarize the existing treatment options and promising new therapies for the prevention and treatment of osteoporosis.