Home > Riviste > Panminerva Medica > Fascicoli precedenti > Panminerva Medica 2002 March;44(1) > Panminerva Medica 2002 March;44(1):73-5

ULTIMO FASCICOLO
 

JOURNAL TOOLS

eTOC
Per abbonarsi
Sottometti un articolo
Segnala alla tua biblioteca
 

ARTICLE TOOLS

Estratti
Permessi

 

CASE REPORTS   

Panminerva Medica 2002 March;44(1):73-5

Copyright © 2009 EDIZIONI MINERVA MEDICA

lingua: Inglese

Delayed ANCA positivity in pulmonary-renal syndrome

Nocente R., Gentiloni Silveri N. *, Bertazzoni G., Ceccanti M. **, Zannoni G. F. ***, Manna R. *, Gasbarrini G. *

From the Emergency Department, University “La Sapienza”, Rome, Italy *Institute of Internal Medicine, Catholic University, Rome, Italy **Institute of Sixth Medical Clinic, University “La Sapienza”, Rome, Italy ***Department of Pathology, Catholic University, Rome, Italy


PDF


A 57-year-old man was admitted due to rapidly progressive renal failure and pulmonary edema. Chest X-ray showed a bilateral lung infiltrate, while a normal myocardial contractility was reported by echocardiography. Though initially ANCA were absent, a necrotizing vasculitis with polymorphonuclear leukocyte infiltrate was observed in a kidney biopsy specimen. Renal histology was compatible with microscopic polyangiitis because of necrotizing lesions located at small vessels and at glomeruli that were not crescentic. Corticosteroids and immunosuppressive treatment was played with significant clinical improvement. Six months later, the patient died of a gastrointestinal hemorrhage due to bowel perforation by vasculitic lesion. This time high p-ANCA positivity was detected and at renal histology crescentic glomeruli were observed.

inizio pagina