CASE REPORTS   

Panminerva Medica 1999 December;41(4):363-6

Copyright © 2000 EDIZIONI MINERVA MEDICA

lingua: Inglese

Extralymphonodal Castleman’s disesase. A case report

Malaguarnera M., Restuccia N., Laurino A., Lo Manto P. C., Vinci E., Pistone G.

From the Institute of Internal Medicine and Geriatrics University of Catania, Catania, Italy

Castleman’s dis­ease is a ­rare ­lymph ­node ­pathology char­ac­ter­ized by angio­fol­lic­ular hyper­plasia. There are two ­forms of the dis­ease: local­ized and ­systemic, ­with dif­ferent fea­tures, symp­toms and prog­nosis. Three are the his­to­log­ical ­types of dis­ease: ­plasma ­cell, hya­line-vas­cular and ­mixed var­i­ants. We ­report the ­case of a 65-year-old ­female ­affected by local­ized ­plasma ­cell var­iant of Castleman’s dis­ease. The sin­gu­larity of our ­case ­lies in its local­iza­tion on the ­breast and mono­clonal ­plasma ­cell pro­life­ra­tion ­inside the ­nodule.