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Panminerva Medica 1999 June;41(2):135-7

Copyright © 2000 EDIZIONI MINERVA MEDICA

lingua: Inglese

Onset of myasthenia gravis in a patient affected by rheumatoid arthritis never treated with disease-modifying anti-rheumatic drugs

Coaccioli S., Ponteggia F., Di Cato L., Allegra A., Puxeddu A.

From the Medical Clinic and Rheumatology University of Perugia, S. Maria Hospital, Terni, Italy


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We ­describe a ­patient affect­ed by rheu­ma­toid ­arthritis (RA) ­that devel­oped myas­the­nia gra­vis (MG) ­after 20 ­years of ill­ness. The pecu­liar­ity of ­this ­case con­cerns ­both the ­rare asso­ci­a­tion ­between ­these dis­eas­es and the ­fact ­that the ­patients had nev­er ­assumed dis­ease mod­i­fy­ing ­antirheu­mat­ic ­drugs. These treat­ments ­have ­been asso­ciat­ed in ­some clin­i­cal ­reports ­with the ­onset of MG dur­ing the clin­i­cal ­course of RA. To our knowl­edge ­this is the ­first ­case ­described in med­i­cal lit­er­a­ture up to now.

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