REVIEWS  DIAGNOSTIC AND THERAPEUTIC MANAGEMENT OF LOCALLY ADVANCED AND ADVANCED PROSTATE CANCER 

The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2015 December;59(4):411-9

Copyright © 2015 EDIZIONI MINERVA MEDICA

lingua: Inglese

Lymph-node relapsed prostate cancer management and PET-driven external beam radiotherapy: salvage or palliative treatment?

Vavassori V. ¹, Alongi F. ², D’agostino G. A. ³, Della Bosca E. ¹, Scorsetti M. ³ ✉

¹ Radiotherapy Unit, Humanitas Gavazzeni, Bergamo, Italy; ² Department of Radiation Oncology, Sacro Cuore Hospital, Negrar, Verona, Italy; ³ Radiotherapy and Radiosurgery, Humanitas Cancer Center, Istituto Clinico Humanitas, Rozzano, Milano, Italy

New imaging modalities such as choline- positron emission tomography (PET) or PET/computed tomography (CT) may be useful to identify prostate cancer patients with small volume, limited nodal relapse (“oligo-recurrent”), potentially amenable to metastasis directed treatment (e.g. radiotherapy,) with the aim of long-term control of the disease, even in a setting traditionally considered prognostically unfavorable, so usually gone to palliative treatment.
This report reviews the diagnostic tools and the main published data about the role of PET or PET/CT driven radiation therapy, (not only for the diagnosis, but also for the plannig) in relapsed node prostate carcinoma, as an alternative therapeutic strategy than surgery or androgen deprivation therapy.