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FOREWORD  NON-STANDARD PET NUCLIDES 

The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2008 June;52(2):134-9

Copyright © 2008 EDIZIONI MINERVA MEDICA

lingua: Inglese

Sustainable production of orphan radionuclides at Wisconsin

Nickles R. J. 1, Avila-Rodriguez M. A. 1, Nye J. A. 2, Houser E. N. 1, Selwyn R. G. 1, Schueller M. J. 3, Christian B. T. 1, Jensen M. 1

1 Medical Physics Department University of Wisconsin, Madison, WI, USA 2 Emory University, Atlanta, GA, USA 3 Brookhaven National Laboratory, Upton, NY, USA 4 Hevesy Laboratory, Risoe Natational Lab Technical University of Denmark, Roskilde, Denmark


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Over a hundred proton-induced reactions have been studied at the University of Wisconsin Medical Physics department since the installation of the first CTI RDS 112 in 1985. The focus has been to measure thick target yields at 11 MeV, in an effort to concentrate on the practical production of positron emitting radionuclides that have favorable decay characteristics, high yields and the potential for labeling pivotal biological tracers. This review covers our recent advances to scale-up the production of the heavy halogens and transition metals as feed-stock for non-conventional PET tracers that are currently attracting increased attention in oncology.

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