Home > Riviste > The Quarterly Journal of Nuclear Medicine and Molecular Imaging > Fascicoli precedenti > The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2006 December;50(4) > The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2006 December;50(4):296-309

ULTIMO FASCICOLO
 

JOURNAL TOOLS

eTOC
Per abbonarsi
Sottometti un articolo
Segnala alla tua biblioteca
 

ARTICLE TOOLS

Estratti
Permessi

 

ADVANCES IN RADIONUCLIDE THERAPY   

The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2006 December;50(4):296-309

Copyright © 2006 EDIZIONI MINERVA MEDICA

lingua: Inglese

Vascular tumor targeting

Ahlskog J. 1, Paganelli G. 2, Neri D. 1

1 Institute of Pharmaceutical Sciences ETH Zurich, Zurich, Switzerland 2 European Institute of Oncology, Milan, Italy


PDF


The growth of solid tumors is dependent on their capacity to acquire blood supply. Therefore, much effort has been directed towards the development of anti-angiogenic agents which inhibit the process of neovascularization. More recently, it has become apparent that the targeted destruction of the established tumor vasculature represents a complementary avenue for growing therapeutic opportunities. This review provides evidence that vascular tumor targeting is an effective anti-tumor strategy in animal models. It further describes strategies for the identification of putative tumor vascular targets and discusses future prospects for vascular targeting applications in the clinical setting.

inizio pagina