Home > Riviste > The Quarterly Journal of Nuclear Medicine and Molecular Imaging > Fascicoli precedenti > The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2005 December;49(4) > The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2005 December;49(4):319-24

ULTIMO FASCICOLO
 

JOURNAL TOOLS

eTOC
Per abbonarsi
Sottometti un articolo
Segnala alla tua biblioteca
 

ARTICLE TOOLS

Estratti

 

REVIEWS  CELL LABELING 

The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2005 December;49(4):319-24

Copyright © 2009 EDIZIONI MINERVA MEDICA

lingua: Inglese

The radiopharmaceutical chemistry of 99mTc-tin fluoride colloid-labeled-leukocytes

Tsopelas B.

Nuclear Medicine Department, RAH Radiopharmacy Royal Adelaide Hospital North Terrace, Adelaide, South Australia


PDF


Tc-99m-tin fluoride colloid is a radiotracer used to label patient white cells, for the diagnosis of infection and inflammation. The scintigraphic technique has been employed in routine clinical practice for approximately 20 years in Australia, yet the chemistry of the radiolabeling agent, and the physiological distribution of 99mTc-leukocytes, are not entirely understood. In this review, the physico-chemical characteristics of 99mTc-tin fluoride colloid are discussed, as well as the in vitro and in vivo distribution of 99mTc-tin fluoride-labeled-leukocytes. Furthermore, important animal and human studies are summarized, that emphasize the clinical usefulness of this radiopharmaceutical tracer in nuclear medicine today.

inizio pagina