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JOURNAL OF NEUROSURGICAL SCIENCES

Rivista di Neurochirurgia


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Journal of Neurosurgical Sciences 2017 Feb 15

DOI: 10.23736/S0390-5616.17.03997-2

Copyright © 2017 EDIZIONI MINERVA MEDICA

lingua: Inglese

Are MODIC Type 2 disc changes associated with low-grade infections? A pilot study

Lorenzo DRAGO 1, 2, Carlo L. ROMANÒ 1, Riccardo CECCHINATO 1, Jorge H. VILLAFAÑE 3, Elena, De VECCHI 1, Claudio LAMARTINA 1, Pedro BERJANO 1

1 IRCCS Istituto Ortopedico Galeazzi, Milan, Italy; 2 University of Milan, Milan, Italy; 3 IRCCS Don Gnocchi Foundation, Milan, Italy


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BACKGROUND: The aim of this study is to compare intra-operative cultural examination in patients undergoing elective surgery for low-back pain with Modic 2 changes to patients without Modic signs. The aim of this study is to compare intra-operative cultural examination in patients undergoing elective surgery for low-back pain with Modic 2 changes to patients without Modic signs.
METHODS: Sixteen patients with Modic 2 changes were compared with 23 patients without Modic signs. Pre-operative laboratory tests and intra-operative tissue cultures were performed, according to a standardized procedure.
RESULTS: While no difference was found in pre-operative laboratory tests, intra-operative cultural examination showed positive results in 6/16 (37.5%) Modic 2 patients versus 1/23 (4.3%) in patients without Modic changes (P=0.012).
CONCLUSIONS: Although performed in a limited series of patients, this study supports the hypothesis that some cases of Modic 2 changes might be associated with the presence of low virulent bacteria.


KEY WORDS: Modic - Infection - Lumbar disc herniation - Low-back pain - Surgery

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Drago L, Romanò CL, Cecchinato R, Villafañe JH, Vecchi D, et al. Are MODIC Type 2 disc changes associated with low-grade infections? A pilot study. J Neurosurg Sci 2017 Feb 15. DOI: 10.23736/S0390-5616.17.03997-2 

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mail@villafane.it