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Journal of Neurosurgical Sciences 2000 December;44(4):234-7

Copyright © 2000 EDIZIONI MINERVA MEDICA

lingua: Inglese

Lhermitte Duclos Disease and Cowden Disease: clinical, pathological and neuroimaging study of a case

Barone F. 1, Noubari B. A. 1, Torrisi A. 2, Lanzafame S. 2, Tropea R. 1, Mancuso P. 1

1 Division of Neurosurgery, Azienda Ospedaliera di Rilievo Nazionale, «Garibaldi, Ascoli-Tomaselli, S. Luigi-S. Curro», Catania; 2 Department of Anatomopathology, University of Catania, Catania, Italy


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The ­authors ­report the ­case of a 26-year-old ­female ­patient affect­ed by Lhermitte Duclos dis­ease and Cowden dis­ease. Preoperative MRI ­allowed a cor­rect diag­no­sis ­which was con­firmed by path­o­log­i­cal exam­ina­tion. The ­authors ­stress the pos­sibil­ity ­that Lhermitte Duclos and Cowden dis­ease be a sin­gle phako­mat­o­sis; for ­this rea­son all the ­patients affect­ed by Lhermitte-Duclos ­should be ­screened for the pres­ence of mul­ti­ple hamar­to­mas or malig­nant neo­plas­tic ­lesions typ­i­cal of Cowden dis­ease.

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