Home > Riviste > Minerva Surgery > Fascicoli precedenti > Articles online first > Minerva Chirurgica 2014 May 14

ULTIMO FASCICOLO
 

JOURNAL TOOLS

Opzioni di pubblicazione
eTOC
Per abbonarsi
Sottometti un articolo
Segnala alla tua biblioteca
 

ARTICLE TOOLS

Estratti
Permessi
Share

 

 

Minerva Chirurgica 2014 May 14

Copyright © 2014 EDIZIONI MINERVA MEDICA

lingua: Inglese

Laparoscopic Nissen fundoplication is more effective intreating patients with GERD-related chronic cough than Stretta radiofrequency

Liang W. 1, Wu J. 2, Hu Z. 2, Wang Z. 1, 2, Zhu G. 1, Zhang C. 1

1 Department of Thoracic Cardiovascular Surgery, Xuanwu Hospital, Capital Medical University, Xicheng District, Beijing, P.R. China 2 Center for GERD, The Second Artillery General Hospital of Chinese People’s Liberation Army, Xicheng District, Beijing, P.R. China


PDF


AIM: Chronic cough is the most common extra-esophageal manifestation of gastroesophageal reflux disease (GERD). This study aimed to retrospectively analyze outcomes in patients with GERD-related cough following laparoscopic Nissen fundoplication (LNF) and Stretta radiofrequency (RF) respectively.
METHODS: Medical charts of 83 patients with GERD-related cough that underwent LNF or Stretta RF between 2007 and 2012 were retrieved. Symptom scores (heartburn, regurgitation and cough) and proton pump inhibitors (PPIs) usages were evaluated.
RESULTS: A total of 83 patients with GERD-related cough underwent LNF (n = 35) and Stretta RF (n = 48), and were followed up 36.78±16.12 months (range 13-55 months). During the follow-up, the post-treatment scores were statistically lower as compared with the pre-treatment scores in both groups, while the cough improvement after Stretta was significantly lower than that after LNF (p < 0.001). Besides, 27 (77.1%) patients achieved complete PPI therapy independence after LNF, comparing with 27 (65.1%) after Stretta (p < 0.05). No significant differences in post-treatment complications were observed except for the abdominal distention.
CONCLUSIONS: Even though laparoscopic Nissen fundoplication and Stretta are capable of controlling GERD-related cough effectively and safely in selected patients, laparoscopic Nissen fundoplication could improve more in symptoms and PPI elimination.

inizio pagina