Home > Riviste > Minerva Surgery > Fascicoli precedenti > Minerva Chirurgica 2019 February;74(1) > Minerva Chirurgica 2019 February;74(1):14-8

ULTIMO FASCICOLO
 

JOURNAL TOOLS

eTOC
Per abbonarsi PROMO
Sottometti un articolo
Segnala alla tua biblioteca
 

ARTICLE TOOLS

Publication history
Estratti
Permessi
Per citare questo articolo
Share

 

ORIGINAL ARTICLE   

Minerva Chirurgica 2019 February;74(1):14-8

DOI: 10.23736/S0026-4733.18.07456-4

Copyright © 2018 EDIZIONI MINERVA MEDICA

lingua: Inglese

Preoperative vitamin D levels do not relate with the risk of hypocalcemia following total thyroidectomy. A cohort study

Alexis DEFFAIN, Federica SCIPIONI, Beatriz DE RIENZO, Sana ALLAL, Marion CASTAGNET, Jean-Louis KRAIMPS, Gianluca DONATINI

Department of General and Endocrine Surgery, CHU Poitiers, University of Poitiers, Poitiers, France



BACKGROUND: Hypocalcemia is the most common complication following total thyroidectomy. Few factors may relate with increased risk of postoperative hypocalcemia. Preoperative vitamin D values have been evaluated in few studies, but reports present conflicting data. Aim of our study is to evaluate the association of preoperative vitamin D values and hypocalcemia following total thyroidectomy.
METHODS: A retrospective analysis of patients undergoing total thyroidectomy in our department of endocrine surgery between November 2012 and November 2015 was performed.
RESULTS: Mean age of patients was 56.2 years (±14.0) and sex ratio (F:M) was 4.3:1. Sixty-four patients (17.4%) had preoperative vitamin D insufficiency (x<25 nmol/L), 138 patients (37.5%) vitamin D deficiency (2550 nmol/L). Following total thyroidectomy for both benign and malignant pathology, 66 patients (17.9%) had symptomatic hypocalcemia (x<2.0 mmol/L) requiring medical treatment (group 1), 64 patients (17.4%) biochemical hypocalcemia (22.1 mmol/L, group 3). Mean postoperative PTH value was 25.4 pg/ml (range 2-61). No statistical correlation between postoperative serum calcium and preoperative vitamin D values (R=-0.001, P=0.9849) was found nor associations were found regarding age, sex, type of thyroid disease or BMI.
CONCLUSIONS: In our cohort of patients, preoperative vitamin D levels were not associated with a higher risk of hypocalcemia following total thyroidectomy. Postoperative PTH appears to be the most sensible item to predict the risk of postoperative symptomatic hypocalcemia.


KEY WORDS: Thyroidectomy - Hypocalcemia - Vitamin D

inizio pagina