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MINERVA STOMATOLOGICA

Rivista di Odontostomatologia e Chirurgia Maxillo-Facciale


Official Journal of the Italian Society of Odontostomatology and Maxillofacial Surgery
Indexed/Abstracted in: CAB, EMBASE, Index to Dental Literature, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index


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Minerva Stomatologica 2018 Mar 08

DOI: 10.23736/S0026-4970.18.04095-5

Copyright © 2018 EDIZIONI MINERVA MEDICA

lingua: Inglese

Orthodontics and Moebius syndrome. An observational study

Marisabel MAGNIFICO 1 , Diana CASSI 1, Mauro GANDOLFINI 1, Andrea TOFFOLI 1, Piero A. ZECCA 2, Alberto DI BLASIO 1

1 Centro Universitario di Odontoiatria, Dipartimento di Medicina, Università di Parma, Parma, Italy; 2 Dipartimento di Biotecnologie e Scienze della Vita, Università dell’Insubria, Como, Italy


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BACKGROUND: Moebius syndrome is a rare condition characterized by bilateral facial and abducens nerve paralysis. The aim of this study is to evaluate the main orthodontic features and the frequency of associated clinical characteristics in patients with Moebius Syndrome (MS).
METHODS: According to Terzis classifications, 58 patients with MS aged 8 months to 46 years old underwent orthodontics and clinical examination.
RESULTS: Strabismus, upper and lower limb malformations, lip and palatal cleft were frequently associated with MS. Reduced TMJ movements were noted (48%). Cephalometric analysis did not allow identifying a typical facies and a characteristic cephalometric pattern; we have noticed a higher prevalence of Class II (56%) with micrognathia and excessive maxillary development probably due to the lack of lip seal. Early treatment is recommended, with a multidisciplinary approach to reduce the impact of sequelae on the lives of MS patients or their families.
CONCLUSIONS: Early treatment is recommended, with a multidisciplinary approach to diminish the impact of sequelae on the lives of MS patients or their families.


KEY WORDS: Moebius syndrome - Orthodontics - Early treatment

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Publication History

Article first published online: March 8, 2018
Manuscript accepted: March 5, 2018
Manuscript revised: February 5, 2018
Manuscript received: August 27, 2017

Per citare questo articolo

Magnifico M, Cassi D, Gandolfini M, Toffoli A, Zecca PA, Di Blasio A. Orthodontics and Moebius syndrome. An observational study. Minerva Stomatol 2018 Mar 08. DOI: 10.23736/S0026-4970.18.04095-5

Corresponding author e-mail

marisabel.magnifico@libero.it