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Minerva Stomatologica 2014 Jan 14


lingua: Inglese

The benefits of Quercitin for dentistry and maxillofacial surgery: a systematic review

Corega C. 1, 2, Vaida L. 3, Festila D. G. 4, Rigoni G. 5, Albanese M. 5, D’agostino A. 5, De Santis D. 5, Pardo A. 6, Nocini P. F. 5, Bertossi D. 5

1 Department of Orthodontics, University Paris V Renee Descartes, Paris, France; 2 University of Medicine and Pharmacy, Iuliu Hatieganu, Cluj-Napoca, Romania; 3 Department of Dental Medicine, Faculty of Medicine and Pharmacy University of Oradea, Oradea, Romania; 4 Department of Orthodontics, University of Medicine and Pharmacy,“Iuliu Hatieganu”, Cluj-Napoca, Romania; 5 Section of Dentistry and Maxillofacial Surgery, Department of Surgery, University of Verona, Verona, Italy; 6 Dental Hygienist, Section of Dentistry and Maxillofacial Surgery, Department of Surgery, University of Verona, Verona, Italy


Quercetin (3,3’,4’,5,7-pentahydroxyflavone) is the major bioflavonoid in the human diet and belongs to an extensive class of polyphenolic flavonoid compounds almost ubiquitous in plants and plant food sources. The estimated average daily dietary intake of quercetin by an individual in the United States is 25 mg. In recent years, research about quercetin has evolved from animal studies to in vitro and in vivo studies and to human clinical studies and trials in order to establish its real properties and effects. In oral medicine, quercetin has been extensively studied, as a real increase in major diseases like cancers, periodontal disease, oral lesions, tooth decay and infections have been reported worldwide by health providers.It has been thus established that quercetin exhibits beneficial effects on oral health with its broad pharmacological properties, as preventive and therapeutic agent in dental caries with anti-inflammatory effect against oral pathogens, as well as an antioxidant and anti-cancer agent .The aim of the review is to present evidence-based aspect of treatment with quercetin in order to validate its tremendous role in dentistry and maxillofacial surgery.

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