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Rivista di Odontostomatologia e Chirurgia Maxillo-Facciale

Official Journal of the Italian Society of Odontostomatology and Maxillofacial Surgery
Indexed/Abstracted in: CAB, EMBASE, Index to Dental Literature, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index




Minerva Stomatologica 2017 December;66(6):248-54

DOI: 10.23736/S0026-4970.17.04075-4


lingua: Inglese

Aspartate aminotransferase activity in peri-implant mucositis: experimental peri-implant mucositis model of 14 days

Blerina ZEZA 1 , Andrea PILLONI 1, Gabriella ANGIULLO 2, Francesco MALATESTA 2, Claudio MONGARDINI 1

1 Section of Periodontics, School of Dentistry, Department of Dentistry and Maxillofacial Surgery, Sapienza University of Rome, Rome, Italy; 2 Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy


BACKGROUND: Experimental peri-implant mucositis has been studied from various prospective in a duration of 21 days. Given the higher sensitivity of peri-implant mucosa the aim of the present study was to evaluate if a duration of 14 days would be sufficient to establish a state of measurable inflammation.
METHODS: Twenty patients of age 57±11-year-old contributed with 20 clinically healthy implants and teeth. They were instructed to use an individual stent in the selected elements prior to performing oral hygiene for 14 days. For each element plaque index (PlI), probing depth (PD), bleeding on probing (Bops) were reported at 0 days and 14 days of plaque accumulation. Aspartate aminotransferase activity was measure at both time points from the crevicular fluid.
RESULTS: Both implant and teeth developed similar increased response of inflammation at 14 days compared to day 0: BoPs of 4.2±1.8 (P=0.06) and BoPs of 3.1±2.2 (P=0.048) for implant and tooth, respectively. Implant presented deeper pocket depth at both time periods but less plaque accumulation. AST activity did not increased significantly, but it was significantly higher at implant level.
CONCLUSIONS: Forteen days of plaque accumulation seemed to be sufficient for the establishment of peri-implant mucositis. However, AST did not resulted as a proper indicator of initial peri-implant inflammation.

KEY WORDS: Gingivitis - Aspartate aminotransferase - Mucositis

inizio pagina

Publication History

Issue published online: November 22, 2017
Article first published online: October 3, 2017
Manuscript accepted: September 26, 2017
Manuscript revised: July 27, 2017
Manuscript received: March 25, 2017

Per citare questo articolo

Zeza B, Pilloni A, Angiullo G, Malatesta F, Mongardini C. Aspartate aminotransferase activity in peri-implant mucositis: experimental peri-implant mucositis model of 14 days. Minerva Stomatol 2017;66:248-54. DOI: 10.23736/S0026-4970.17.04075-4

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