Home > Riviste > Minerva Pneumologica > Fascicoli precedenti > Minerva Pneumologica 2019 March;58(1) > Minerva Pneumologica 2019 March;58(1):1-6

ULTIMO FASCICOLO
 

JOURNAL TOOLS

eTOC
Per abbonarsi
Sottometti un articolo
Segnala alla tua biblioteca
 

ARTICLE TOOLS

Publication history
Estratti
Permessi
Per citare questo articolo

 

ORIGINAL ARTICLE   

Minerva Pneumologica 2019 March;58(1):1-6

DOI: 10.23736/S0026-4954.18.01838-2

Copyright © 2018 EDIZIONI MINERVA MEDICA

lingua: Inglese

Investigating diagnostic accuracy, sensitivity, and specificity of body plethysmography for the diagnosis of pulmonary function disorder

Hanieh RAJI 1, Maryam HADDADZADEH SHOUSHTARI 1, Mohammad KARAMI BAVANDPURI 1, Neda MAKVANDI 2

1 Air Pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; 2 Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran



BACKGROUND: Cardiopulmonary exercise testing (CPET) technique monitors the response of exercise to pulmonary, cardiovascular, hematopoietic, nervous, and musculoskeletal systems as well as metabolic and endocrine systems. Since this test is expensive and is not available everywhere, its alternative is body plethysmography. Body plethysmography test is cheaper, its technique is easier, is available everywhere, and its interpretation is simpler than CPET. The aim of the study was to investigate the diagnostic accuracy, sensitivity, and specificity of body plethysmography for the diagnosis of pulmonary function disorder.
METHODS: This prospective cross-sectional study was conducted on 60 workers of Ahwaz Steel Complex with respiratory disorder or abnormal spirometry from 2017 to 2018. Demographic information of these patients were recorded. All patients were placed in body box and respiratory volumes (RV, TLC, RV-TLC, FEV1, FVC, FEV1/FVC) were measured. Also, on the day of referral to the lung specialist, both body box CPET tests were performed. All patients were placed under CPET and parameters (VO2max, anaerobic threshold, breath reserve, heart rate reserve, heart rate, O2 pulse, and work load) related to this test were recoded and interpreted and data were analyzed using SPSS v. 22.
RESULTS: The mean age patients were 38.13±7.07. There was no statistically significant difference between demographic factors between patients. Spirometry test showed that the average of FEV1 was 75.57±11.38, FVC: 83.80±11.77, FEV1/FVC: 76.49±7.63, VC: 75.36±12.6, FEF 25-75%: 65.41±16.16, FEV1/VCmax: 0.75±0.06 and obstructive pattern (31.66%) diagnosed more than other patterns. Average results of body plethysmography test parameters showed average of RV was 109±26.97, TLC: 93.47±12.16 and RV/TLC was 112.93±18.70 so obstructive pattern (48.33%) diagnosed more than other patterns. Sensitivity of body plethysmography test was 84.37% and specificity level was obtained as 85.71% and accuracy was obtained as 85%. Positive and negative predictive values of body plethysmography test were 87.9% and 82.75%, respectively and positive and negative likelihood ratios were obtained as 5.9 and 0.18, respectively.
CONCLUSIONS: Body plethysmography test has high sensitivity in diagnosing disorder and disease in patient and using this test, most of healthy people were diagnosed correctly and the probability to diagnose healthy and sick patients with this test is high.


KEY WORDS: Whole-body plethysmography - Respiratory function tests - Exercise test

inizio pagina