REVIEW  NOVEL INSIGHTS INTO PEDIATRIC ALLERGY AND IMMUNOLOGY Free access

Minerva Pediatrica 2020 October;72(5):358-63

DOI: 10.23736/S0026-4946.20.05967-8

Copyright © 2020 EDIZIONI MINERVA MEDICA

lingua: Inglese

Pidotimod in allergic diseases

Sara MANTI ✉, Giuseppe F. PARISI, Maria PAPALE, Salvatore LEONARDI

Unit of Pediatric Respiratory, Department of Clinical and Experimental Medicine, AOU Vittorio Emanuele Polyclinic, San Marco Hospital, University of Catania, Catania, Italy

The rising incidence of allergic disease requires more specific, effective and safe therapeutic strategies. In this regard, several kinds of biologically active substances, commonly known as immunostimulants, have been introduced for the prevention and treatment of allergic diseases in pediatric population. Among the heterogeneous group of biologically active molecules to date available, pidotimod (Axil, Valeas S.p.A, Milan) is proved to be able to ameliorate both innate and adaptive immunity and enhances the immune system properties often impaired in patients with allergic disorders.

KEY WORDS: Asthma; Dermatitis, atopic; Child; Chronic urticaria; Pidotimod; Rhinitis