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Minerva Pediatrica 2019 April;71(2):150-8
DOI: 10.23736/S0026-4946.18.05449-X
Copyright © 2018 EDIZIONI MINERVA MEDICA
lingua: Inglese
Enterovirus and parechovirus infections in children: differences in clinical presentation, mechanisms for meningitis without pleocytosis and mechanisms involved in the neurological outcome
Stephanie C. de CROM ✉
Department of Pediatrics, Bravis Hospital, Roosendaal, The Netherlands
Enterovirus (EV) and Parechovirus (HPeV) are a frequent cause of infection in children. This review gives an overview of possible causes for differences in clinical presentation. EV and HPeV can cause a meningitis with or without pleocytosis. Different possible mechanisms for meningitis without pleocytosis are given. Little is known about the prognosis and long-term effects of EV and HPeV meningitis in children. Only some studies with a small number of children with EV or HPeV meningitis are reported. The different possible mechanisms involved in the neurological outcome after EV or HPeV meningitis will be discussed.
KEY WORDS: Enterovirus - Parechovirus - Child - Infection