REVIEW   

Minerva Pediatrica 2017 June;69(3):225-9

DOI: 10.23736/S0026-4946.16.04713-7

Copyright © 2016 EDIZIONI MINERVA MEDICA

lingua: Inglese

Pediatric cardiovascular risk factors

Jing TIAN, Xinjiang AN✉, Mingyu FU

Department of Pediatrics, Xuzhou Children’s Hospital, Xuzhou, China

The dominant cause of mortality, morbidity and hospitalization worldwide is cardiac complications, and are the major public health problem in adult populations. The worldwide research is being focused on the idea that cardiovascular disease is an early life pathological state. Early unfavorable exposures, acting in different periods of fetal and early postnatal life, have been observed to be responsible for permanent editions in the cardiac system. This idea has been confirmed by preclinical experimental studies confirming the early life growth restriction leading to developmental adaptations in cardiovascular form and system. All these editions results in elevated susceptibility to cardiovascular disease. The present review article will put emphasis on these risk factors, which lead to the deadly cardiac pathology state in young infants.

KEY WORDS: Cardiovascular diseases - Pediatrics - Risk factors