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REVIEW   

Minerva Pediatrica 2018 August;70(4):396-402

DOI: 10.23736/S0026-4946.17.04874-5

Copyright © 2017 EDIZIONI MINERVA MEDICA

lingua: Inglese

Pediatric mesenchymal stromal cells therapy: an update

Qi AN, Conghai FAN , Shumei XU

Department of Internal Medicine, Xuzhou Children’s Hospital, Xuzhou, China


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The mesenchymal have heterogeneous composition and till date no single, definitive marker for their identification is available. Further, this cell population is identified by their adherence to plastic, spindle-like morphology and their trilineage plasticity. They also have ability to differentiate into bone, cartilage and fat. Moreover, MSC as “multipotent stromal cells” is a preferred choice over “mesenchymal stem cells”, as the later definition includes many cell populations, several of which do not fulfill the self-renewal and multi-lineage potential of true stem cells. So, the present review article is focused to enlighten recent views of MSC therapy in the field of Pediatrics.


KEY WORDS: Pediatrics - Mesenchymal stromal cells - Therapy

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