Home > Riviste > Minerva Pediatrica > Fascicoli precedenti > Minerva Pediatrica 2018 April;70(2) > Minerva Pediatrica 2018 April;70(2):151-8



Publication history
Per citare questo articolo


Rivista di Pediatria, Neonatologia, Medicina dell’Adolescenza
e Neuropsichiatria Infantile

Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,764




Minerva Pediatrica 2018 April;70(2):151-8

DOI: 10.23736/S0026-4946.16.04300-0


lingua: Inglese

Echocardiographic changes and growth retardation in a group of Egyptian children with rheumatic heart disease

Nayera E. HASSAN 1, Hala S. HAMZA 2, Wael A. ATTIA 2 , Moenes M. ABU SHADY 3, Omar H. DWIDAR 1

1 Department of Biological Anthropology, National Research Center, Giza, Egypt; 2 Division of Pediatric Cardiology, Department of Pediatrics, Cairo University Children Hospital, Cairo, Egypt; 3 Department of Child Health, National Research Centre, Giza, Egypt


BACKGROUND: Advances in echocardiographic studies have identified a massive burden of rheumatic heart disease (RHD) which continues to be a major health hazard in most developing countries. The aim of this study was to investigate the correlation between cardiac affection as regards the presence of single or multiple valvular lesions, and their severity and the growth parameters in a group of Egyptian children with RHD.
METHODS: This study is a cross-sectional study, that was conducted on 200 children with RHD and 400 age-matched healthy. All subjects were subjected to anthropometric measurement and echocardiographic evaluation of the different cardiac parameters.
RESULTS: Isolated mitral incompetence (MI) was the most frequent type of valvular lesion in RHD (54.0%), followed by mixed MI and aortic incompetence (AI) (26.5%). Patients with RHD were more liable to be underweight and stunted compared to controls (P<0.05). Growth retardation was significantly noticed in patients with RHD in general (P<0.05), and particularly in patients mixed MI and AI in particular (P<0.05). Also a significant association was detected between growth retardation and the severity of the valvular lesion in the group of rheumatic heart patients (P<0.05).
CONCLUSIONS: Associations between growth retardation and RHD with its various patterns of valvular affection and severity were detected in the present study.

KEY WORDS: Rheumatic heart disease - Heart valves - Growth disorders

inizio pagina

Publication History

Issue published online: February 2, 2018
Article first published online: November 17, 2016
Manuscript accepted: August 12, 2015
Manuscript revised: June 22, 2015
Manuscript received: March 15, 2015

Per citare questo articolo

Hassan NE, Hamza HS, Attia WA, Abu Shady MM, Dwidar OH. Echocardiographic changes and growth retardation in a group of Egyptian children with rheumatic heart disease. Minerva Pediatr 2018;70:151-8. DOI: 10.23736/S0026-4946.16.04300-0

Corresponding author e-mail