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Minerva Obstetrics and Gynecology 2021 Apr 20

DOI: 10.23736/S2724-606X.21.04734-5


lingua: Inglese

Assessment of morbidity and mortality in newborns with late prematurity: experience of a reference maternity in the northeast of Brazil

Liliana S. PAES 1, Francisco H. CARVALHO 1, Edward ARAUJO JÚNIOR 2 , Helvécio N. FEITOSA 1

1 Department of Maternal and Child Health, Federal University of Ceará (UFC), Fortaleza-CE, Brazil; 2 Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo-SP, Brazil


BACKGROUND: Late preterm infants show high rates of adverse perinatal outcomes. The aim of this study is to assess the morbidity and mortality of newborns (NBs) with late preterm birth in a reference maternity hospital in northeastern Brazil.
METHODS: Retrospective cohort study from March 1 to July 15, 2017. A total of 204 NBs with gestational age between 34 and 36 weeks and six days were evaluated and compared to 205 full-term NBs (39 and 40 weeks and six days). Perinatal outcomes including neonatal morbidity were evaluated. The Student’s t and ANOVA tests were used for normal variables, and the Wilcoxon, Mann-Whitney and Kruskal-Wallis tests for non-normal variables.
RESULTS: Late preterm infants showed significant higher rates of hypothermia, hypoglycemia, respiratory distress syndrome, jaundice in need of phototherapy (67.6%), admission to the neonatal intensive care unit (ICU), and difficulty breastfeeding compared to full-term NBs (p<0.001). Respiratory distress was the main indication for the admission of late preterm infants (p<0.001) to neonatal ICU. Late preterm infants had a longer hospital stay (6.9 vs. 3.7 days, p<0.001). There were three deaths in the group of late preterm NBs, and none in the group of term NBs.
CONCLUSIONS: Late preterm NBs presented higher rates of morbidity and mortality when compared to full-term NBs.

KEY WORDS: Morbidity; Mortality; Newborns; Late preterm birth

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