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Minerva Ginecologica 2020 February;72(1):50-4

DOI: 10.23736/S0026-4784.20.04494-9

Copyright © 2020 EDIZIONI MINERVA MEDICA

lingua: Inglese

The impact of primary Sjogren’s syndrome on female sexual function

Maria G. PICCIONI, Lucia MERLINO, Marianna DEROMA, Federica DEL PRETE, Sara TABACCO , Marco MONTI, Pierluigi BENEDETTI PANICI

Department of Obstetrics and Gynecology, Sapienza University, Rome, Italy



INTRODUCTION: Sjogren syndrome (SS) is a chronic autoimmune disease that usually affects women more than man with a 9:1 ratio. It leads to a progressive functional impairment of exocrine glands. Tipically, its clinical presentation is characterized by xerostomia and xerophtalmia, but it can also affect, among others, female genital apparatus, causing vaginal dryness and dyspareunia.
EVIDENCE ACQUISITION: PubMed and Google Scholar were searched for articles in English indexed from January 1995 to November 2019 to assess evidence on the impact of primary Sjogren’s syndrome on female sexual function. Our attention was directed specifically on the quality of sexual life of patients affected by primary SS.
EVIDENCE SYNTHESIS: SS is associated with sexual dysfunction and it can significantly worsen patient’s quality of life.
CONCLUSIONS: The genital disorders secondary to SS can strongly alter the quality of female life both physically and psychologically as they alter sexuality. However, the observation of certain behavioral norms and the use of appropriate local substances can alleviate the symptoms and effectively contribute to reducing the discomfort.


KEY WORDS: Sjogren’s syndrome; Dyspareunia; Sexual dysfunction, physiological

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