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Rivista di Ostetricia e Ginecologia

Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index




Minerva Ginecologica 2018 April;70(2):138-43

DOI: 10.23736/S0026-4784.17.04102-8


lingua: Inglese

Is pH a vaginal health marker? Phemale Study

Santiago PALACIOS 1 , Silvia P. GONZÁLEZ 2, Maria J. CANCELO 3

1 Palacios Institute for Women’s Health and Medicine, Madrid, Spain; 2 Gabinete Velázquez Polyclinic, Madrid, Spain; 3 Guadalajara General Hospital, Guadalajara, Spain


BACKGROUND: Epidemiological data regarding vaginal pH in Spain are scarce. An epidemiological study was therefore undertaken to confirm the physiological pattern of vaginal pH in Spanish women. The primary outcome measure was vaginal pH. Secondary outcomes included the relationship between vaginal pH and BMI, physical activity, working status, contraceptive use, sexual intercourse in the two days prior to the visit and clinical vaginal symptoms.
METHODS: Cross-sectional study in which 2136 healthy women over 18 years of age who requested a check-up were recruited. Vaginal pH was determined using specific for pH testing. Results were compared using Spearman’s correlation test and ANOVA.
RESULTS: The mean vaginal pH observed in the different age groups was 4.82 in women aged under 30, 5.10 in those aged between 30 and 35, 5.11 in those aged 36 to 40, and 6.48 in those aged over 55. No association was found between vaginal pH and BMI or sexual intercourse in the two previous days. Lower vaginal pH values were observed in women with some degree of physical activity and in contraceptive users, with higher vaginal pH values observed in women who presented clinical symptoms (P<0.01).
CONCLUSIONS: This study confirms the physiological patterns of vaginal pH changes in Spanish women. Any degree of physical activity and the use of contraceptives were associated with lower pH values. The presence of vulvo-vaginal symptoms was related with higher vaginal pH values. Vaginal pH is a marker of vaginal health.

KEY WORDS: Hydrogen-ion concentration - Physiology - Pathophysiology - Age factors

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Publication History

Issue published online: February 2, 2018
Article first published online: September 5, 2017
Manuscript accepted: August 30, 2017
Manuscript received: June 7, 2017

Per citare questo articolo

Palacios S, González SP, Cancelo MJ. Is pH a vaginal health marker? Phemale Study. Minerva Ginecol 2018;70:138-43. DOI: 10.23736/S0026-4784.17.04102-8

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