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Minerva Dental and Oral Science 2021 Oct 21

DOI: 10.23736/S2724-6329.21.04606-4

Copyright © 2021 EDIZIONI MINERVA MEDICA

lingua: Inglese

Efficacy of bio-activated anti-calculus toothpaste on oral health: a single-blind, parallel-group clinical study

Edoardo BRAUNER 1, Michele DI COSOLA 2, Mariateresa AMBROSINO 2, Angela P. CAZZOLLA 2, Mario DIOGUARDI 2, Riccardo NOCINI 3, Skender TOPI 4, Antonio MANCINI 5, Maria E. MAGGIORE 5, Salvatore SCACCO 6, Lucrezia BOTTALICO 7, Annarita MALCANGI 8, Stefania CANTORE 5

1 Department of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Roma, Italy; 2 Department of Clinical and Experimental Medicine, Università degli Studi di Foggia, Foggia, Italy; 3 Section of Ear Nose and Throat (ENT), Department of Surgical Sciences, Dentistry, Gynecology and Pediatric, University of Verona, Verona, Italy; 4 School of Technical Medical Sciences, A. Xhuvani University, Elbasan, Albania; 5 Department Interdisciplinary of Medicine, University of Bari Aldo Moro, Bari, Italy; 6 Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy; 7 Interdepartmental Research Center for Pre-Latin, Latin and Oriental Rights and Culture Studies (CEDICLO), University of Bari Aldo Moro, Bari, Italy; 8 Azienda Sanitaria Locale BAT, Trani, Italy


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BACKGROUND: Current epidemiologic studies have confirmed the widespread presence of calculus in teenagers and adults of all ages. Among the multiple anti-calculus strategies that have been proposed over the years inhibition of crystal growth has been the most attractive. Current formulations in anti-calculus toothpastes and mothwash, utilise either hydroxyapatite or various pyrophosphate combinations. This study aimed to analyze the efficacy of an anti-calculus tooth paste in combination or not with a mouth rinse.
PATIENTS AND METHODS: Patients (totally 40) used a pyrophosphate-based toothpaste containing Tetrapotassium Pyrophosphate, Pentasodium Triphosphate, Xylitol, Hydroxyapatite, Citric Acid, And Calcium Carbonate (Group A) in combination, with a mouth rinse containing an association of Pentasodium Triphosphate, Tetrapotassium Pyrophosphate and Citric Acid (Group B). A range of parameters were measured for: saliva pH, Volpe Manhold Calculus Index (VMI), Gingival Index (GI), and Plaque Index (PI).
RESULTS: The test mouth rinse Group B showd reductions in VMI, GI, PI, and increases in pH levels, after using the combination of toothpaste and mouth rinse. No changes to the mucosa or teeth were observed in both Groups. Patients perceived that the comitation of products was more effective.
CONCLUSIONS: The results from the three-month calculus examination indicated that both the tested products, modified positively clincal parameters and salivary pH. Moreover, the use of the tested products was not associated with any adverse effects.


KEY WORDS: Oral health; Salivary pH; Volpe manhold calculus index; Gingival and plaque index

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