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Minerva Chirurgica 2018 Apr 12

DOI: 10.23736/S0026-4733.18.07425-4


lingua: Inglese

Mucopexy-Recto Anal Lifting (Mu-RAL): a standardized minimally invasive method of managing symptomatic hemorrhoids, with an innovative suturing technique and the HemorPex System®

Claudio PAGANO 1 , Contardo VERGANI 2, Carlo INVERNIZZI 1, Massimo BUSSONE 1, Guido BENEGIAMO 1, Marco VENTURI 2

1 Presidio Ospedaliero Vizzolo Predabissi ASST Milano-Martesana, UOC Chirurgia Generale, Vizzolo Predabissi, Milan, Italy; 2 Department of Pathophysiology and Transplantation, Ospedale Maggiore Policlinico Fondazione IRCCS Ca’ Granda, UOSD Day/Week Surgery, Università degli Studi di Milano, Milan, Italy


BACKGROUND: Conservative surgery of hemorrhoidal disease is less painful than traditional hemorrhoidectomy, and mucopexy has less risk of serious postoperative complications than stapled hemorrhoidopexy. The aim of this study was to evaluate the safety and effectiveness of a standardized, modified hemorrhoidopexy, named Mucopexy-Recto Anal Lifting (MuRAL),with the HemorPex System (HPS) in patients with symptomatic III and IV degree hemorrhoids.
MATERIALS AND METHODS: Patients were enrolled from May 2013 to Dec 2015 and operated on with the MuRAL technique, based on arterial ligation and mucopexy at 6 locations, using a standardized clockwise/anti-clockwise rotation sequence of the HPS anoscope. Follow-up controls were carried out by independent observers, as follows: a digital exploration 3 weeks after the intervention, digital exploration plus proctoscopy at 3 and 12 months and repeated at a 12 months interval. Patients who did not strictly follow the postoperative controls were excluded from the study. Primary outcome measurement was the recurrence rate. Secondary measurements were: operative time, hospital stay, postoperative pain, postoperative symptoms and satisfaction score.
RESULTS: We operated on 126 patients (72 males, mean age 53.9, range 29-83): 87 (69.6%) with III degree and 39 with IV degree hemorrhoids; 13 patients had a MuRAL as a revisional procedure of a previous operation for hemorrhoids. Mean duration of follow up was 554 days (range 281-1219). Four patients were excluded from the study. One-year recurrence rate was 5.1%. The mean duration of the intervention was 29.5 minutes (range 23-60) and 92 patients (73%) were discharged during the same day of the operation. Pain VAS score in the first, second and third postoperative day was 3.9, 2.5, and 1.9, respectively. Twenty-two patients (18 %), all submitted to spinal anesthesia, had postoperative acute urinary retention. Fecal urgency, observed in 18.8 % of patients at the first control, disappeared within one year after the operation. Mean time to return to normal activity was 8 days (range 5 -10). The patient satisfaction scores at one-year follow up were 31.1 % excellent, 57.4% good, 7.4% fairly good and 4.1% poor. In patients with III degree hemorrhoids operative time was significantly shorter, postoperative pain better and transient fecal urgency lower than in IV degree patients.
DISCUSSION: In our experience the standardization of MuRAL operation with HPS, turned out to be a safe and effective minimally invasive approach in managing symptomatic III and IV degree hemorrhoids , avoiding the risk of severe complications, with the possibility to perform a redo-MuRAL in the event of recurrence. In our series up to 88% of the patients reported a good, or excellent one-year satisfaction score. Further comparative randomized studies with longer follow-up period are needed.

KEY WORDS: Hemorrhoidal disease - Mucopexy - Recto-anal lifting - HemorPex system

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Publication History

Article first published online: April 12, 2018
Manuscript accepted: April 6, 2018
Manuscript revised: February 19, 2018
Manuscript received: June 6, 2017

Per citare questo articolo

Pagano C, Vergani C, Invernizzi C, Bussone M, Benegiamo G, Venturi M. Mucopexy-Recto Anal Lifting (Mu-RAL): a standardized minimally invasive method of managing symptomatic hemorrhoids, with an innovative suturing technique and the HemorPex System®. Minerva Chir 2018 Apr 12. DOI: 10.23736/S0026-4733.18.07425-4

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