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Minerva Chirurgica 2017 Feb 23

DOI: 10.23736/S0026-4733.17.07292-3


lingua: Inglese

Polylactide-caprolactone composite mesh used for ventral hernia repair: a prospective, randomized, single-blind controlled trial

Ying-Mo SHEN, Qi LI, Jie CHEN, Li SUN, Fu-Qiang CHEN

Department of Hernia and Abdominal Wall Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China


BACKGROUND: Although composite surgical meshes are widely used in laparoscopic repair of ventral hernia, the risk of postoperative complications associated with these type of mesh is relatively high. In this report, we demonstrated the safety as well as the effectiveness of a new composite polypropylene mesh coated with poly Llactidecocaprolactone ε (EasyProsthesTM) for the repair of ventral hernia.
METHODS: This study was a randomized, controlled trial designed to compare EasyProsthes composite mesh (EPM) with ParietexTM Composite (PCO) in patients undergoing laparoscopic ventral hernia repair. Hernia recurrence, chronic pain, seroma formation, intestinal fistula or obstruction, wound or abdominal infection, and viscera adhesion were evaluated. 80 patients who needed repair surgery for primary or secondary ventral hernias were enrolled in this study. Patients were divided into two groups: the EPM group (n=40) and the PCO group (n=40). Patients completed 12 months of followup.
RESULTS: Our results revealed that one patient in the EPM group (2.5%) and two patients in the PCO group (5%) developed mesh viscera adhesions after surgery (p=1.000). We had no case of intestinal fistulas or obstruction. Seventeen patients in EPM group (42.5%) and 21 in PCO group (52.2%) developed post surgical seromas in the surgery area (p=0.370). One patient from each group developed postoperative wound infection. There was no case of abdominal infection, chronic pain or hernia recurrence. The incidence of postoperative complications in the EPM group was similar to that observed in the PCO group.
CONCLUSIONS: We concluded that EPM is a safe and effective method to be used in ventral hernia repair surgeries.

KEY WORDS: Ventral hernia repair - Surgical composite mesh - Randomized control trial

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Shen YM, Li Q, Chen J, Sun L, Chen FQ. Polylactide-caprolactone composite mesh used for ventral hernia repair: a prospective, randomized, single-blind controlled trial. Minerva Chir 2017 Feb 23. DOI: 10.23736/S0026-4733.17.07292-3 

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