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Minerva Cardiology and Angiology 2021 Oct 29

DOI: 10.23736/S2724-5683.21.05710-0


lingua: Inglese

Atrial function analysis after percutaneous umbrella device and suture-mediated patent fossa ovalis closure

Carmela TARSIA 1, Carlo GASPARDONE 2, Gregory A. SGUEGLIA 1, Antonella DE SANTIS 1, Emanuela D’ASCOLI 1, Fabiana PICCIONI 1, Maria IAMELE 1, Giuseppe A. POSTERARO 1, Alessandra CINQUE 1, Achille GASPARDONE 1

1 U.O.C. Cardiologia, Ospedale Sant’Eugenio, Rome, Italy; 2 Vita-Salute San Raffaele University, Milan, Italy


BACKGROUND: Atrial fibrillation is an undesirable event following percutaneous patent fossa ovalis (PFO) closure with metallic occluders, suggesting that implanting a rigid closure device could alter atrial function Suture-mediated PFO closure is a new technique, achieving closure of the PFO by means of a simple suture. Aim of this study was to evaluate left atrial function after closure of PFO by direct suture and traditional occluders.
METHODS: We studied 40 age and sex homogeneous patients, 20 undergoing PFO closure by device (OCL) and 20 by suturing (NS). Twenty healthy sex-age matched subjects made up the control group (CT). Left atrial function was evaluated by using volumetric and speckle-tracking analysis assessing the following parameters: Total Emptyng Fraction (EF), Expansion index (EI), Active Emptyng Fraction (AEF), strain values of the reservoir (r-ED), conduit (cd-ED) and contraction phase (ct-ED).
RESULTS: Compared to CT and NS, OCL patients had significantly worst indices of left atrial reservoir function (EF p=0.001, EI p=0.003, r-ED p <0.001), conduit function (cd-ED p=0.018) and contraction function (AEF p=0.010; ct-ED p <0.001). No significant differences were observed in left atrial function indices between CT and NS patients.
CONCLUSIONS: Suture-mediated PFO closure does not alter left atrial function. Conversely, metallic occluder is associated with worse left atrium function This detrimental effect on atrial function could favor the development of atrial arrhythmias.

KEY WORDS: Patent fossa ovalis; Atrial function; NobleStitch EL system; Occluder device

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