ORIGINAL ARTICLE   

Minerva Cardiology and Angiology 2021 April;69(2):133-40

DOI: 10.23736/S2724-5683.20.05109-9

Copyright © 2020 EDIZIONI MINERVA MEDICA

lingua: Inglese

Association between ST-segment resolution after primary angioplasty and short-term outcomes in patients with acute myocardial infarction

Fatemeh MASOUMKHANI ¹, Sepehr GOHARI ², Tara RESHADMANESH ², Hassan AHANGAR ¹ ✉, Soghrat FAGHIHZADEH ³

¹ Department of Cardiology, Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran; ² School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran; ³ Department of Epidemiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

BACKGROUND: The aim of this study was to evaluate the relationship between the early/late complete ST-resolution and short-term cardiovascular outcomes in patients undergoing primary angioplasty.
METHODS: This was a prospective cross-sectional study of patients with acute myocardial infarction who candidate for primary percutaneous coronary intervention (PCI) during 1 year. An ECG obtained at the time of admission, 90 minutes and 24 hour after PCI. Patients were followed up for in hospital and 1-year outcomes and then data assessed according to the ST segment resolution (STR) (complete ≥70% and incomplete <70% STR).
RESULTS: Overall, 124 patients included in the study. The rates of complete STR were 44.4% after 90 minutes and 82.3% after 24 hours. Patients with early complete STR had significant lower rates of heart failure after 1-year follow-up (32% versus 46%, OR: 1.88, 95% CI: 1.42-2.50, P=0.005) but not like patients with late STR. No significant relationship was observed between early/late complete STR and re-infarction, stroke, re-hospitalization and death during 1-year follow-up (P>0.05). Moderate correlations were found between percentage of ST resolution after 90 minutes and EF before discharge and final EF (correlation coefficient: 0.395 and 0.488, respectively, P<0.001).
CONCLUSIONS: Early complete STR can be an indicator for development of heart failure after 1-year follow-up.

KEY WORDS: Myocardial infarction; Coronary balloon angioplasty; Treatment outcome