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REVIEW STEMI: CURRENT KNOWLEDGE AND FUTURE PERSPECTIVES
Minerva Cardioangiologica 2018 August;66(4):442-51
DOI: 10.23736/S0026-4725.18.04614-5
Copyright © 2018 EDIZIONI MINERVA MEDICA
lingua: Inglese
How the functional assessment of culprit and non-culprit lesions may improve stratification and treatment of STEMI patients
Gianluca CAMPO 1, 2, 3 ✉, Francesco GALLO 1, Giulia BUGANI 1, Rita PAVASINI 1, Massimo FINESCHI 4
1 Cardiovascular Institute, Ferrara University Hospital, Cona, Ferrara, Italy; 2 Maria Cecilia Hospital, GVM Care and Research, Ettore Sansavini Health Science Foundation, Cotignola, Ravenna, Italy; 3 Department of Cardiovascular Diseases, Santa Maria alle Scotte, University Hospital, Siena, Italy
Reperfusion therapy of the infarct-related artery (IRA) with primary percutaneous coronary intervention is the cornerstone for the treatment of patients with ST-elevation myocardial infarction (STEMI). However, up to 30% of STEMI patients present a multi-vessel coronary artery disease. Several methods are now available for the assessment of functional severity of a coronary stenosis both for IRA and non-culprit coronary lesions. The functional assessment of the IRA has mainly a prognostic implication in terms of major adverse cardiovascular events, recovery of left ventricular function and evaluation myocardial viability. Conversely, the functional assessment of the non-culprit coronary lesions has a fundamental role to guide staged revascularization. The aim of this review is to revise the most validated methods to perform the functional assessment of both culprit and non-culprit lesion in ST-elevation myocardial infarction.
KEY WORDS: Myocardial fractional flow reserve - Hyperemia - ST elevation myocardial infarction