REVIEW   

Minerva Biotecnologica 2018 December;30(4):120-9

DOI: 10.23736/S1120-4826.18.02466-7

Copyright © 2018 EDIZIONI MINERVA MEDICA

lingua: Inglese

Optical coherence tomography in early detection of malignancies

Farah ANDLEEB ^{1, 2}, Hafeez ULLAH ¹ ✉

¹ Department of Physics, Bio-Photonics Research Laboratory, The Islamia University of Bahawalpur, Bahawalpur, Pakistan; ² Department of Physics, Govt. Sadiq College Women University, Bahawalpur, Pakistan

In this review article, we explore the mechanisms of optical coherence tomography (OCT) and its applications in various skin diseases. OCT is a novel real-time imaging modality based on Michelson interferometry of infrared radiation and living tissues. This technique permits the high resolution of 2 and 3-dimensional cross-sectional microvasculature imaging of tissues and surveillance over time. The major purpose of this review article is to explore OCT imaging of skin tumors, oral tumors, tumor angiogenesis, and choroidal tumors with early phase detection.

KEY WORDS: Tomography, optical coherence - Dermatology - Blood vessels - Imaging, three-dimensional