MEDICINAL PLANTS FOR BIOTECHNOLOGY AND BIOMEDICINE 

Minerva Biotecnologica 2005 September;17(3):127-31

Copyright © 2006 EDIZIONI MINERVA MEDICA

lingua: Inglese

The role of metabolic engineering for the production of secondary metabolites of plants

Khan M. T. H. ^{1, 2}, Ather A. ², Gambari R. ^{2, 3}

¹ Pharmacology Research Laboratory, Faculty of Pharmaceutical Sciences, University of Science and Technology, Chittagong, Bangladesh; ² ER-GenTech, Department of Biochemistry and Molecular Biology, University of Ferrara, Ferrara, Italy; ³ Biotechnology Center, University of Ferrara, Ferrara, Italy

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Plants are very interesting and useful sources of molecules of great importance for the development of new pharmaceutical products. Metabolic engineering has proven to be a valuable tool for large production of several biomedically as well as industrially relevant compounds from micro-organisms as well from higher plants. Current development of studies employing transgenic and/or recombinant technologies have opened up opportunities of the metabolic engineering/ metabolo-mics of biosynthetic pathways, leading to the growth of manufacturing of high-value secondary metabolites, even at the commercial level.