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MEDICINAL PLANTS FOR BIOTECHNOLOGY AND BIOMEDICINE
Minerva Biotecnologica 2005 September;17(3):127-31
Copyright © 2006 EDIZIONI MINERVA MEDICA
lingua: Inglese
The role of metabolic engineering for the production of secondary metabolites of plants
Khan M. T. H. 1, 2, Ather A. 2, Gambari R. 2, 3
1 Pharmacology Research Laboratory, Faculty of Pharmaceutical Sciences, University of Science and Technology, Chittagong, Bangladesh; 2 ER-GenTech, Department of Biochemistry and Molecular Biology, University of Ferrara, Ferrara, Italy; 3 Biotechnology Center, University of Ferrara, Ferrara, Italy
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Plants are very interesting and useful sources of molecules of great importance for the development of new pharmaceutical products. Metabolic engineering has proven to be a valuable tool for large production of several biomedically as well as industrially relevant compounds from micro-organisms as well from higher plants. Current development of studies employing transgenic and/or recombinant technologies have opened up opportunities of the metabolic engineering/ metabolo-mics of biosynthetic pathways, leading to the growth of manufacturing of high-value secondary metabolites, even at the commercial level.