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Minerva Anestesiologica 2019 October;85(10):1080-8

DOI: 10.23736/S0375-9393.19.13543-2

Copyright © 2019 EDIZIONI MINERVA MEDICA

lingua: Inglese

SOFA Score prognostic performance among patients admitted to High-Dependency Units

Francesca INNOCENTI 1 , Francesca CALDI 1, Irene TASSINARI 1, Federico MEO 1, Arianna GANDINI 1, Paola NOTO 2, Giuseppe MANGANO 2, Giuseppe CARPINTERI 2, Riccardo PINI 1

1 High-Dependency Unit, Department of Clinical and Experimental Medicine, Careggi University Hospital, Florence, Italy; 2 Department of Emergency Medicine, Vittorio Emanuele University Hospital, Catania, Italy



BACKGROUND: The aim of this study was to assess prognostic stratification in patients admitted in two Italian Emergency-Department High-Dependency Units (ED-HDU).
METHODS: From June 2014, to July 2016, we recorded all patients admitted in the ED-HDU of the Careggi University Hospital and the Vittorio Emanuele University Hospital in a standardized database. Charlson Index and SOFA Score were calculated to evaluate comorbidity burden and severity of organ dysfunction. End-points were HDU and in-hospital mortality rate and need of Intensive Care Unit (ICU) transfer.
RESULTS: The overall number of patients admitted in the two Units was 3311, 1822 in Florence and 1489 in Catania. HDU mortality rate was 5% (N.=171); compared with survivors, non-survivors showed a higher SOFA Score (10.0±4.2 vs. 3.5±2.9, P<0.001) and a higher number of organ dysfunctions (1.6±0.9 vs. 0.6±0.8, P<0.001). All patients with a SOFA Score in the first and second quartile survived HDU admission (only two non-survivors among patients in the second quartile), while mortality was disproportionally high in the group with a score value in the fourth quartile (0%, 0.2%, 3% and 14%, P<0.001). Presence and number of organ failure, as well as SOFA Score (5.6±4.0 vs. 3.4±2.8, P<0.001), were significantly higher in patients transferred to ICU than in those admitted in an ordinary ward or discharged. A higher SOFA Score (RR 1.55, 95% CI: 1.47-1.63, P<0.001) was associated with an increased HDU mortality, independent of age and Charlson Index.
CONCLUSIONS: SOFA Score showed a good discrimination ability for both HDU - mortality and indication to increase the level of care.


KEY WORDS: Emergency service, hospital; Diagnosis-related groups; Organ dysfunction Scores

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