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Rivista di Anestesia, Rianimazione, Terapia Antalgica e Terapia Intensiva

Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
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Minerva Anestesiologica 2017 September;83(9):939-46

DOI: 10.23736/S0375-9393.17.11544-0


lingua: Inglese

Prediction of fluid responsiveness based on liver compression-induced blood pressure changes in children after cardiac surgery

Ji-Hyun LEE, In-Kyung SONG, Eun-Hee KIM, Hee-Soo KIM, Jin-Tae KIM

Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, South Korea


BACKGROUND: This study evaluated whether liver compression-induced blood pressure changes can predict fluid responsiveness in children after cardiac surgery.
METHODS: Children aged <5 years who were undergoing cardiac surgery were evaluated after the sternum was closed. Before fluid loading, the right upper abdomen was compressed at a pressure of 30 mmHg for 15 seconds and changes in blood pressure waves were recorded. Then, 10 mL/kg of colloid solution was administered. Systolic arterial pressure (SAP), diastolic arterial pressure (DAP), central venous pressure (CVP), systolic pressure variation (SPV), stroke volume, and respiratory variation in aortic blood flow peak velocity (ΔVpeak) were measured before and after fluid loading. A volume responder was defined as >15% increase in Stroke Volume Index.
RESULTS: There were 17 responders and 13 non-responders. During liver compression, mean percent increase in DAP (ΔDAP) was significantly higher in the responder group (10.5%) than in the non-responder group (5.4%) (P=0.008). A ΔDAP of 5% during liver compression and a ΔVpeak of >12% were able to predict fluid responsiveness (P=0.01 and 0.02, respectively). However, changes in SAP during liver compression, SPV, and CVP had no predictive value. The area under the receiver operating characteristic curve of ΔDAP and ΔVpeak were 0.778 and 0.765, respectively.
CONCLUSIONS: ΔDAP induced by liver compression and ΔVpeak can be used to predict fluid responsiveness in mechanically ventilated children. Liver compression can be a simple and practical method to assess volume status in children.

KEY WORDS: Blood pressure - Cardiac output - Echocardiography - Fluid therapy - Stroke volume

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Publication History

Issue published online: September 5, 2017
Article first published online: March 8, 2017
Manuscript accepted: March 7, 2017
Manuscript revised: January 26, 2017
Manuscript received: July 7, 2016

Per citare questo articolo

Lee JH, Song IK, Kim EH, Kim HS, Kim JT. Prediction of fluid responsiveness based on liver compression-induced blood pressure changes in children after cardiac surgery. Minerva Anestesiol 2017;83:939-46. DOI: 10.23736/S0375-9393.17.11544-0

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