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Minerva Anestesiologica 2011 April;77(4):468-9

Copyright © 2011 EDIZIONI MINERVA MEDICA

lingua: Inglese

Vascular injury following accidental intra-arterial injection of clindamycin: adverse drug reaction report

Lehavi A. 1, Sandler A. 1, Netzer A. 2, Katz Y. S. 1, 3

1 Department of Anesthesiology, Rambam Health Care Campus, Haifa, Israel; 2 Ear, Nose and Thought and Head and Neck Surgery, Rambam Health Care Campus, Haifa, Israel; 3 Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel


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Clindamycin in a commonly used antibiotic, considered safe for oral, intravenous and intra-arterial use. We present a case of a patient that received an inadvertent injection clindamycin 600 mg in 4 mL through a radial arterial line. The patient presented signs and symptoms of vascular occlusion and despite aggressive pharmacological and medical treatment developed massive and severe tissue injury.

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