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Minerva Anestesiologica 2009 July-August;75(7-8):467-70

Copyright © 2009 EDIZIONI MINERVA MEDICA

lingua: Inglese

Fatal subarachnoid hemorrhage from mycotic aneurysm ruptures in an immunocompetent patient with aspergillosis: a case report

Del Gaudio A. 1, Catapano D. 2, Pagano A. 1, Zagaria G. 1, Sorrentino E. 1, D’Angelo V. 2

1 Department of Anesthesia and Intensive Care, “Casa Sollievo della Sofferenza” Hospital, San Giovanni Rotondo, Foggia, Italy; 2 Department of Neurosurgery, “Casa Sollievo della Sofferenza” Hospital, San Giovanni Rotondo, Foggia, Italy


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Cerebral aspergillosis is a rare condition usually encountered in severely immunodepressed patients. We review the case of an immunocompetent patient who developed a fulminant form of cerebral aspergillosis which led to death due to the rapid formation and rupture of multiple mycotic aneurysms in the cerebral arteries. We suggest the possible role of genetic factors in causing this unusual clinical history and we propose that cerebral aspergillosis should be taken into consideration early in the process of diagnosis in order to allow for timely treatment.

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