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Rivista di Angiologia

Official Journal of the International Union of Angiology, the International Union of Phlebology and the Central European Vascular Forum
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International Angiology 2018 Jan 25

DOI: 10.23736/S0392-9590.18.03950-0


lingua: Inglese

The influence of exercise on ulcer healing in patients with chronic venous insufficiency


Surgery & Cancer, Imperial College London, London, UK


BACKGROUND: Venous Leg Ulcer (VLU) affects millions of people, and yet there have been no major advances in its treatment for many decades. Is it the time to change our approach, and try a multidisciplinary one that could bring about a change. The aim of this study is to evaluate whether a regular, home-based exercise could be influential in healing the VLU.
METHODS: 80 subjects (mean age: 65.13 years) were recruited for 12 weeks. The participants were randomised into a control group (n=20), a compression therapy group (n=20), an exercise group (n=20) and a compression and exercise group (n=20). The exercise comprised of 10 dorsiflexions each hour while the patient was awake. The first 2 groups did not perform any exercise while the other two did. Baseline and 3-month measurements were performed. These mesrements include skin perfusion assessment and ulcer size.
RESULTS: All patients showed low tcPO2 in the beginning of the study. At the point of 3 months of execise, Laser Doppler flowmetry and ulcer size measurements showed significant decrease, p < 0.001 in exercise groups, however, no real change was demonstrated in the non-exercise groups. Subjects who were performing exercise showed significant increase in tcPO2 readings after 3 months (p< 0.001), whereas the tcPO2 readings remained the same in the non-exercise groups.
CONCLUSIONS: We concluded that exercise had a significant effect on the VLU healing and this effect may be enhanced further with the help of the compression therapy. The tcPO2 and RF measurements may be seen as useful tools in evaluating the microvascular changes, and monitoring healing and follow up of the venous leg ulcer.

KEY WORDS: Venous - Exercise - Ulcer

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Publication History

Article first published online: January 25, 2018
Manuscript accepted: January 11, 2018
Manuscript received: November 12, 2017

Per citare questo articolo

Mutlak O, Aslam M, Standfield N. The influence of exercise on ulcer healing in patients with chronic venous insufficiency. Int Angiol 2018 Jan 25. DOI: 10.23736/S0392-9590.18.03950-0

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