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International Angiology 2002 September;21(3):233-6

Copyright © 2003 EDIZIONI MINERVA MEDICA

lingua: Inglese

Gravity of aortic arch calcification as evaluated in adult Greek patients

Symeonidis G., Papanas N., Giannakis I., Mavridis G., Lakasas G., Kyriakidis G., Artopoulos I.

Second Department of Internal Medicine, “O Agios Dimitrios” Hospital, Thessaloniki, Greece * Radiology Department, “O Agios Dimitrios” Hospital, Thessaloniki, Greece


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Background. The aim of the ­present study was to evaluate the grav­ity of aor­tic arch cal­cifi­ca­tion in adult Greek ­patients.
Methods. A total of 1027 ­patients (498 men, 529 women) were includ­ed. Aortic arch cal­cifi­ca­tion was ­assessed by means of pos­te­roan­ter­i­or chest X-rays. These were stu-d­ied by two radiol­o­gists blind­ed to the ­patients’ med­i­cal ­records. Calcification was grad­ed as fol­lows: grade 0 (no vis­ible cal­cifi­ca­tion), grade 1 (small spots of cal­cifi­ca­tion or sin­gle thin cal­cifi­ca­tion of the aor­tic knob), grade 2 (one or more areas of thick cal­cifi­ca­tion), grade 3 (cir­cu­lar cal­cifi­ca­tion of the aor­tic knob). All ­patients were clin­i­cal­ly and elec­tro­car­di­o­graph­i­cal­ly exam­ined for cor­o­nary ­artery dis­ease. The other param­e­ters includ­ed in the anal­y­sis were age, sex, smok­ing, body-mass index, hyper­ten­sion, dys­lip­i­de­mia, dia­betes mel­lit­us and his­to­ry of ­stroke.
Results. Calcification grav­ity was grade 0 in 421 ­patients (41%), grade 1 in 308 ­patients (30%), grade 2 in 216 ­patients (21%) and grade 3 in 82 ­patients (8%). In sim­ple regres­sion anal­y­sis the grav­ity of aor­tic arch cal­cifi­ca­tion was pos­i­tive­ly cor­re­lat­ed with age (p=0.01), dia­betes mel­lit­us (p=0.014), hyper­ten­sion (p=0.022), dys­lip­i­de­mia (p=0.038) and cor­o­nary ­artery dis­ease (p=0.041). In mul­ti­ple regres­sion anal­y­sis it was asso­ciat­ed with age (p=0.019), dia­betes mel­lit­us (p=0.02) and hyper­ten­sion (p=0.03).
Conclusions. Gravity of aor­tic arch cal­cifi­ca­tion in adult Greek ­patients may eas­i­ly be ­assessed on rou­tine chest X-rays and is pos­i­tive­ly cor­re­lat­ed with cor­o­nary ­artery dis­ease, as well as impor­tant car­di­o­vas­cu­lar risk fac­tors (age, dia­betes mel­lit­us, hyper­ten­sion and dys­lip­i­de­mia).

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