ORIGINAL ARTICLES   

International Angiology 2002 September;21(3):214-7

Copyright © 2003 EDIZIONI MINERVA MEDICA

lingua: Inglese

Albumin-coated knitted Dacron aortic prostheses. Study of postoperative inflammatory reactions

Kudo F. A., Nishibe T., Miyazaki K., Flores J., Yasuda K.

Department of Cardiovascular Surgery, Hokkaido University School of Medicine, Hokkaido, Japan

Background. The pur­pose of this study was to inves­ti­gate the post­op­er­a­tive inflam­ma­to­ry reac­tions to albu­min-coat­ed Dacron ­grafts (ACGs), which are used in the ­repair of abdom­i­nal aor­tic aneu­rysm (AAA).
Methods. Experimental ­design: a ret­ro­spec­tive study with a fol­low-up peri­od of 14 days. Setting: University hos­pi­tal. Patients: 50 ­patients admit­ted for elec­tive AAA ­repair from January 1997 to January 2000. Interventions: each ­patient under­went AAA ­repair with an ACG (Bard, albu­min-coat­ed Dacron graft). Measures: the white blood cell (WBC) count, plas­ma C-reac­tive pro­tein (CRP) con­cen­tra­tion, and body tem­per­a­ture (BT) were deter­mined. The pre­op­er­a­tive data, the high­est val­ues of the post­op­er­a­tive data, and the val­ues 2 weeks postsur­gery were ana­lyzed.
Results. The BT, CRP, and WBC ­increased and ­peaked at the 1st week postsur­gery and then ­decreased grad­u­al­ly. The BT and WBC lev­els ­returned to nor­mal with­in 2 weeks. The CRP level con­tin­ued to show slight­ly ele­vat­ed val­ues in the 2nd week, but it was not sig­nif­i­cant­ly dif­fer­ent com­pared to the pre­op­er­a­tive data.
Conclusions. The use of an albu­min-impreg­nat­ed pros­the­sis for the recon­struc­tion of AAA is bio­com­pat­ible, since no sig­nif­i­cant increas­es in inflam­ma­to­ry reac­tions are ­observed in the 2nd week postsur­gery.