ORIGINAL ARTICLE   

Gazzetta Medica Italiana - Archivio per le Scienze Mediche 2020 October;179(10):564-71

DOI: 10.23736/S0393-3660.20.04100-5

Copyright © 2020 EDIZIONI MINERVA MEDICA

lingua: Inglese

Does moderate intensity aerobic and progressive resisted exercise affect cardiovascular product in persons living with HIV-related distal symmetrical poly-neuropathy?

Abdulsalam M. YAKASAI ✉, Sonill S. MAHARAJ

BACKGROUND: The rate-pressure product (RPP) determines the clinical patency of the heart as it indicates the myocardial oxygen demand. HIV-infected individuals have a high prevalence of coronary heart disease (CHD). Exercise has been advocated for a variety of cardiovascular diseases, with documented improvements in cardiovascular fitness, but there is uncertainty to the persons living with HIV(PLWHIV) related distal symmetrical polyneuropathy (DSPN). This trial aimed to explore the effectiveness of progressive resisted exercise (PRE) or aerobic exercise (AE) on RPP, SBP, and HR in PLWHIV-related DSPN.
METHODS: A convenient sampling technique was used to recruit 154 participants and were randomized equally into AE, PRE, and control group (CG). 136 participants with mean age 36.79±8.23 years completed the study. The interventions consisted of cycle ergometer, quadriceps bench resisted training, and control received no treatment. The data were analyzed using mean (95% CI) and one-way analysis of variance to find out any differences between the three groups.
RESULTS: The result indicates no significant difference between groups at baseline (P>0.05), and significant differences exist in all variables at 12 weeks (P<0.05).
CONCLUSIONS: The findings suggest that AE or PRE is beneficial for PLWHIV and can serve as a useful exercise approach in the management of cardiovascular risk in HIV-related neuropathy.

KEY WORDS: Acquired immunodeficiency syndrome; Polyneuropathies; Coronary disease; Cardiovascular system; Exercise