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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2018 November;177(11):658-60

DOI: 10.23736/S0393-3660.17.03621-X

Copyright © 2017 EDIZIONI MINERVA MEDICA

lingua: Inglese

Extra-lymphatic lymphoma located in the breast, liver and thyroid

Pedram TORABIAN 1, Mohamad DEHESTANI 2, Azra IZANLOO 1, Mohammadreza NASSIRI 3, 4, Mohammad M. KOOSHYAR 5

1 Razavi Cancer Research Center, Razavi Hospital, Imam Reza International University, Mashhad, Iran; 2 Department of Medical Genetic, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; 3 Recombinant Proteins Research Group, The Research Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran; 4 Genetics Subgroup, Department of Animal Science, Ferdowsi University of Mashhad, Mashhad, Iran; 5 Department of Hematology and Oncology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran


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We presented a 42-year-old patient suffering from primary non-hodglein’s lymphoma in breast, liver and thyroid. The patient referred to a clinic complaining about nausea, jaundice, feeling of mass in the right breast, abdominal pain, fever and weight loss. Based on the clinical symptoms, valproate sodium treatment with perfenazine was administered to him. The results of biopsy revealed low malignant NHL breast. Moreover, the results of liver and thyroid biopsy also indicated NHL. Thus, chemotherapy was performed for the patient. The patient is still alive 16 years after the treatment without any major problem. The main purpose for presenting this case was to describe and introduce a case of primary lymphoma in breast, liver and thyroid. Physicians should be suspicious of the primary lymphoma outside of its usual sites (lymph nodes) and administer supplementary tests for patients who have clinical symptoms similar to NHL, but their laboratory factors remain unchanged and mediastinum and lymph nodes are not involved. It should be noted that thyroid, breast and liver can be the site of extra-lymphatic lymphoma.


KEY WORDS: Lymphoma - Breast - Liver - Thyroid gland

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